| Team Transactions |
| DATE | TRANSACTION |
| January 14, 2010 | Announced the resignation of defensive coordinator Dean Pees. |
| January 13, 2010 | Signed TE Robbie Agnone, TE Rob Myers, DL Adrian Grady, DL Darryl Richard, WR Darnell Jenkins and QB Jeff Rowe. LB Junior Seau announced his retirement. |
| January 6, 2010 | Placed WR Wes Welker on injured reserve. Signed LB Thomas Williams from the practice squad. Signed WR Nick Moore and WR Robert Ortiz to the practice squad. Placed WR Darnell Jenkins on the practice squad-injured list. |
| December 9, 2009 | Signed DL Titus Adams from the practice squad. Placed CB Bret Lockett on injured reserve. Signed QB Jeff Rowe and WR Darnell Jenkins to the practice squad. |
| November 11, 2009 | Signed LB Thomas Williams to the practice squad. |
| November 6, 2009 | Released G Kendall Simmons. |
| October 21, 2009 | Released WR Joey Galloway and TE Michael Matthews. |
| October 15, 2009 | Signed LB Junior Seau. Released DL Terdell Sands. |
| September 24, 2009 | Signed C Ryan Wendell to the practice squad. Released OT Patrick Brown from the practice squad. |
| September 23, 2009 | Acquired LB Prescott Burgess from Baltimore for a conditional seventh-round draft pick. |
| September 8, 2009 | TE Robert Agnone added to practice squad |
| September 7, 2009 | WR Greg Lewis cut; S Bret Lockett acquired from waivers; DT Titus Adams added to practice squad; WR Terrence Nunn added to practice squad; DT Darryl Richard added to practice squad; OT Patrick Brown added to practice squad; DT Adrian Grady added to practice squad; WR Isaiah Stanback added to practice squad; CB DeAngelo Willingham added to practice squad |
| September 6, 2009 | S Bret Lockett cut; OG Kendall Simmons signed/unrestricted free agent |
| September 5, 2009 | OT Patrick Brown cut; WR Isaiah Stanback cut; CB DeAngelo Willingham cut; DT Adrian Grady cut; DT Titus Adams cut; CB Jamar Love cut; WR Terrence Nunn cut; DT Darryl Richard cut; TE Robert Agnone cut; OT Wesley Britt cut; S Herana-Daze Jones cut; LB Paris Lenon cut; S Raymond Ventrone cut; TE Michael Matthews acquired via trade from the New York Giants |
| September 4, 2009 | WR Robert Ortiz cut; S Roderick Rogers cut; DT Steve Williams cut; LB Vinny Ciurciu cut; QB Andrew Walter cut; G Billy Yates cut; G Matt McChesney cut |
| August 31, 2009 | LB Tedy Bruschi retired; C Nathan Hodel cut; OT Mark LeVoir placed on PUP list; LB Tyrone McKenzie placed on PUP list; WR Brandon Tate placed on PUP list; G Darnell Stapleton placed on PUP list; OT Marvel Smith placed on PUP list |
| August 26, 2009 | Signed wide receiver Robert Ortiz. |
| August 26, 2009 | Traded offensive lineman Russ Hochstein to the Denver Broncos for an undisclosed draft choice; signed linebacker Tyrone McKenzie; released safety Tank Williams. |
| August 23, 2009 | Released tight end Tyson DeVree. |
| August 19, 2009 | Signed safety Roderick Rogers. |
| August 18, 2009 | Signed running back Chris Taylor; placed wide receiver Shun White on the reserve/military list; traded defensive lineman Le Kevin Smith to the Denver Broncos for an undisclosed draft pick. |
